By Carl Strohmeyer-PAMR 35+ years experience
Updated 10-21-16

Obviously the starting place is aquarium disease prevention, but many readers will be too late to this aspect of fish husbandry, which is the point of this particular article.
A good article for prevention of aquarium disease is this one:
"Aquarium Disease Prevention; Proven Steps for a Healthy Aquarium"
Every single step in the above article should be followed to a T and I can guarantee that the incidence of disease will go down greatly.
Hopefully readers will acquaint themselves with this above referenced article which will in part form a basis for this article as I go forward.
As well this article is another good read before one goes forward with any fish treatment:
"Aquarium Medications; Part 1"

A good analogy I like to use as to why it is so important to eliminate these issues is this:
"Not correcting causes or background issues is akin to standing in a burning building asking for a treatment for burns, while not leaving the burning building"

Often this is not because the person does not want to, but they simply do not have the means or the availability for whatever reason to do so.
I would also point out, and while this may seem a bit harsh, it is still the reality, and that is this is still not a valid excuse to continue to ask for alternative treatments or complain to persons such as myself that the treatment failed when proper procedures have not been completely followed.
I personally spend a copious amount of time writing articles, answering questions, or even paying staff to help for free, but please remember that one needs to obviously follow the medication course prescribed, but just as importantly if not more so, deal with ALL underlying causes to a given fish illness problem. So repeatedly going in circles when not following exactly advice given is in my opinion disrespectful to the person who is trying to help you with your fish illness issue.
Here first are basic procedures to check off before treating any fish sickness issue:
- Make sure ALL water parameters are as they should be. This includes well known and obvious parameters as well as less obvious parameters.
INCLUDING:- Ammonia; under .5 ppm (best .25 or less)
- Ph; stable within the generally accepted target range of the fish to be kept (if the target range is 6.5 to 7.5, stable at any number there-in)
- KH; this too can vary depending upon fish kept, but generally anywhere from 50 ppm to 150 ppm
- Flow and oxygen levels; most persons do not have an oxygen test kit, so having a water flow turnover rate of 5 times for an average non-planted freshwater aquarium usually will indicate adequate oxygen levels
- Redox and Mineral Cations; this is an aspect of fish care that continued research both in and out of the hobby/industry is proving to be key.
In diseases such as Columnaris, having a less than optimum Redox whether it be the electromagnetism of the water, missing mineral Cations, low water rH, or simply too many free radicals (oxidizers) making for an unbalanced Redox; this is a major aspect in whether you will be successful in treating or just as importantly not have this disease present in the first place (since it is an opportunistic infection).
Further Reading; Aquarium Redox
- Follow ALL professional based treatment regimens when you treat for a disease.
This includes full dose of medications for the recommended days, any baths, swabs or similar if required, increased or decreased water temperatures if required, and use of sodium chloride salt if required (as an example, the last two are required for Columnaris treatment).
In other words, it a fish bath, dip, or bare isolation/hospital tank is called for in the treatment regimen, this should be used, otherwise do not expect optimum results.
Further Reading:
Aquarium Answers article about Fish Baths - Follow ALL recommended fish husbandry aspects of fish care, including water changes, good filtration (including true germicidal filtration), proper mineralization, feeding, even optimal tank size, tank mates and places to hide from aggressive tank mates (example would be a small Mbuna/African Cichlid aquarium with little rock structures for weaker/submissive fish to escape, which can result in stressor that allow a disease such as Columnaris to get a foothold and then even spread to stronger fish in this aquarium).
I have addressed this in part in the overview section of this article, but since optimal aquarium conditions are one of the key aspects of most ALL fish disease treatments, I will note this again and expand a little more on it.
A common line I hear from well meaning aquarium keepers or even well meaning persons giving advice is: "Yes, my water conditions are good, I feed a good fish food, & I used what you stated".
Then I dig deeper and I find out that only part of a treatment is followed, they did not maintain a stable KH, proper mineralization and Redox, and what they assumed was a good fish food is what the person at PetsMart told them was best or they purchased from a large online marketer such as Amazon.
Even if a person has a UV Sterilizer, it often turns out to be just a Clarifier such as a "Green Killing Machine" or the many HOB UV filters they purchased on Amazon that might be great for green water, but does little to address disease prevention.
I cannot emphasize more the reading of these articles:
*"Aquarium Disease Prevention; Proven Steps for a Healthy Aquarium"
*"Aquarium Redox Balance"
*"Aquarium UV Sterilization; Facts & Information"
*"Fish Nutrition"
Next, here are causes for failure of any fish illness treatment regimen:

- My first thought here is to point out that even a Medical Doctor with her/his years of college and later internship and experience along with the medical equipment and test at her/his disposal cannot cure everything, but not addressing underlying issues only complicates any human medical treatment further. An analogy here is a patient who asks the doctor why he/she had a heart attack at only 42 years old, but fails to recognize the doctors advice that he/she is obese and needs to stop eating a Big Mac burger for breakfast, lunch, & dinner.
The other aspect of this bullet point is even is you were to follow everything correctly, have all the resources possible, and remove underlying causes; success is NEVER guaranteed. - Failure to follow medication treatment regimen or substitutions for what ever reason.
Reference: "Aquarium Medications; Part 1" - Genetics & poor breeding.
This is more common than many know, especially with fish such as Betta and goldfish which are heavily inbred for certain attributes with fish physiology be damned, thus resulting in very genetically weak fish (think about how many pedigree dogs are also over bred). - Poor care such as over crowding with resulting high ammonia exposure at some time in the life of the fish resulting in permanent organ damage that makes a fish susceptible to disease and treatment difficult later in life.
This is common with carnival goldfish, but again common with Bettas in how they are shipped and kept right up to their purchase. - Poor Diet.
This also does not need to be a current poor diet, it can be a past poor diet (and in fact generally is since diet issues rarely show up immediately).
Diet issues include renal (Kidney) failure due to incorrect or poorly optimized protein levels, too low fiber, and fatty liver disease from too high of energy levels again instead of optimum levels (optimum is 280 energy points).
These are unfortunately quite common as even most of the best of fish food diets that use top notch ingredients do NOT optimize! This is even a bigger problem with most common fish foods fed.
A few examples as per exceeding optimum energy levels are: New Life Spectrum at 329, Cobalt Fish Foods at 420, and Wardleys' at a whopping 501 energy points!Unfortunately once the fish is sick due to past poor diets, even improved diets often cannot correct the issue, thus resulting in failure of treatment. This is especially true for Dropsy and other causes of bloating and even for Columnaris.
Reference: Fish Nutrition
Recommended Fish Food:
AAP Custom Premium Optimized Fish Food

Other Recommended Reference & Product Sites

AAP Hydro Sponge Filters
THE PREMIUM Aquarium Sponge Filter with as much as 5 TIMES the bio and mechanical capacity of commonly sold Chinese knock offs!!
Definitely worth the extra $1-3

For TRUE High Output, Hot Cathode, Low Pressure UVC Germicidal Bulbs, for aquarium or pond

NilocG High Growth Liquid Plant Ferts
NilocG Aquatics PROFESSIONAL GRADE planted aquarium liquid fertilizer products. Products designed for persons who want to have a more advanced planted aquarium without the hassles need for a degree in science to do so. Meant for use in "The Estimative Index of Dosing, or No Need for Test Kits" method of planted aquarium aquascaping. Products work for both low light and high light planted aquariums, just different dosages.
PUR or RQE, YouTube Video Fail- Guide to lighting a planted tank

AquaRay Ultra Premium Aquarium LED Lights
Highest in PUR, The ONLY LED with an IP67 rating or higher for water proofing along with a full 5 year warranty to back them up! Why purchase brands without this rating such as the Finnex, Current, or Fluval only to be essentially placing an electronic light emitting device over your humid aquarium with little or no guarantee? In the long term, you WILL PAT MORE!
TMC V2 RO Filter systems; the very best you can buy with TDS meter (far superior to 4 stage RO/DI systems sold via Bulk Reef Supply, Amazon, or eBay that use the inferior cellulose triacetate membrane made by Dow):


Hanna Instruments Aquarium Testers & Meters; For Freshwater and Saltwater
Hanna instruments is a global manufacturer of analytical instrumentation. Hanna offers multi-parameter bench top portable meters and testers..